Precision Surgery and Genomics

Precision surgery aligns operative decisions with a patient’s molecular profile, anatomy, and physiology—so treatment is targeted, tissue-sparing, and outcome-focused. This session shows how to integrate biomarkers, imaging phenotypes, and predictive models into procedure selection, margin strategy, and perioperative care. We translate sequencing reports into actionable pathways, explain when tumor boards change the surgical plan, and demonstrate how phenotype–genotype matching improves function and survival across specialties. If you’re looking for Precision Surgery & Genomics, planning to attend a Surgical Science Conference, or exploring advances in surgical genomics, this page details practical steps to connect molecular insights with incision-time choices.

We cover pre-op mapping that blends radiomics and high-resolution imaging with genomic risk; intra-op fluorescence, navigation, and real-time pathology that guide margins; and post-op plans aligned with targeted adjuvant therapies. You’ll learn when minimally invasive or organ-preserving tactics are safe, how to use sentinel mapping and nodal genomics to refine staging, and how to counsel patients about benefits and tradeoffs in plain language. We emphasize equity—making precision accessible with panel selection that matters, cost-aware testing, and turnaround workflows that don’t delay surgery. Education content includes tumor board playbooks, inter-disciplinary consult scripts, and documentation that ties decisions to evidence. Finally, we look ahead to single-cell analytics, liquid biopsy for surveillance, and AI that fuses images, waveforms, and omics into decision support. Participants leave with a checklist to standardize precision pathways from clinic to OR to follow-up—grounded in safety, value, and shared decision-making.